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What Do You Know about the Diabetic Nephropathy?

Read |Information source:SJZ kidney disease hospital|Published:2016-02-20

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diabetic nephropathy is a clinical syndrome characterized by the following:

Persistent albuminuria (>300 mg/d or >200 μg/min) that is confirmed on at least 2 occasions 3-6 months apart

Progressive decline in the glomerular filtration rate (GFR)

Elevated arterial blood pressure (see Workup)

Proteinuria was first recognized in diabetes mellitus in the late 18th century. In the 1930s, Kimmelstiel and Wilson described the classic lesions of nodular glomerulosclerosis in diabetes associated with proteinuria and hypertension.

By the 1950s, kidney disease was clearly recognized as a common complication of diabetes, with as many as 50% of patients with diabetes of more than 20 years having this complication.

Currently, diabetic nephropathy is the leading cause of chronic kidney disease in the United States and other Western societies. It is also one of the most significant long-term complications in terms of morbidity and mortality for individual patients with diabetes. Diabetes is responsible for 30-40% of all end-stage renal disease (ESRD) cases in the United States.

Generally, diabetic nephropathy is considered after a routine urinalysis and screening for microalbuminuria in the setting of diabetes. Patients may have physical findings associated with long-standing diabetes mellitus. Good evidence suggests that early treatment delays or prevents the onset of diabetic nephropathy or diabetic kidney disease.

Regular outpatient follow-up is key in managing diabetic nephropathy successfully.

Article URL:http://www.sjzkidney.com/disease/dn/1059.html

TAG:Diabetic Nephropathy

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