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How Can We Make Sure Whether Patients with Protein+++ in Urine Have Nephrotic Syndrome or not?

Read |Information source:SJZ kidney disease hospital|Published:2016-02-01

How can we make sure whether patients with protein+++ in urine have nephrotic syndrome or not? Firstly, from the kidney problem aspects, the leaking of protein is caused by the damage of filtering function of kidneys. For patients with nephrotic syndrome, protein+++ is the manifestation of nehrotic syndrome. When patients have protein+++, they should be cautious, because protein+++ indicates that their illness condition is still deteriorating.

How can we make sure whether patients with protein+++ in urine have nephrotic syndrome or not? What are the symptoms of nephrotic syndrome? Patients with nephrotic syndrome are called “three high and one low”, that is high protein in urine, high blood fat, high swelling and low protein in blood. Followings, our specialist will give you a further explanation of the symptoms of nephrotic syndrome.

1. High protein in the urine: high protein in the urine is the obvious mark for patients with nephrotic syndrome. The protein in urine mainly include albumin, also include plasma proteins. The permeability change of glomerular basement membrane is the root cause of protein in the urine; the change of electrostatic barrier and mechanical barrier, the reabsorb and catabolism ability of epithelial cell of kidney tubules have influence to the formation of protein in the urine.

2. Hypoproteinemia: Hypoproteinemia is the second characteristics of nephrotic syndrome. The serum protein is less than 30g/L. The synthesis of albumin by liver increase for patients with nephrotic syndrome, and when the diet for patients include enough protein and calories, the amount of synthesis protein by liver every day is about 22.6g, which is obvious more than patients who don’t have nephrotic syndrome. When the protein synthesized by liver can not make up the lost protein, hypoproteinemia occurs. Hypoproteinemia and protein in urine are full accordance.

3. Hyperlipidaemia: the total cholesterol and triacylglycerol increase obviously; low density lipoprotein increase. Patients with hyperlipidaemia and low albumin may have lipid urine in which there is birefringence fat.

4.swelling: the most obvious symptoms for patients with nephrotic syndrome are swelling, in the first stage, the swelling can occur in eyelid, face, ankles; with the development of illness, the swelling can spread over body and along with chest dydrops, ascites, hydropericardium, mediastinal encapsulated effusion, scrotum or labia swelling, sometimes lung swelling occur.

How can we make sure whether patients with protein+++ in urine have nephrotic syndrome or not? After reading the test above, you may have a fully understand of nephrotic syndrome.

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